General Information |
|
Product |
Phospho PDE3B Antibody BIOTIN |
Description |
BIOTIN-Conjugated Phosphorylated Phosphodiesterase 3B Antibody N-epitope |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Chicken, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 260-310 on rat PDE3B protein. Selective for only PDE3B variant |
Accession # |
NCBI: EDM17772.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
1.0-1.25 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. |
Molecular Function |
Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding |
Subcellular Location |
Membrane; Multipass membrane protein |
Expression |
Abundant in adipose tissues. |
Structure |
Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6 (By similarity). |
Alternative Nomenclature |
5''-cyclic phosphodiesterase B antibody Adipocyte cAMP phosphodiesterase cGMP inhibited antibody AI847709 antibody cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody CGI-PDE B antibody CGIP1 antibody CGIPDE1 antibody cGMP inhibited 3 5 cyclic phosphodiesterase B antibody HcGIP1 antibody Pde3b antibody Phosphodiesterase 3B cGMP inhibited antibody |
Protein information supplied by UniProt
Fabgennix Phospho-PDE3B Antibody has been used in 2 Publications |
|
Huang, Lei, et al. "Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury." The Journal of Neuroscience 35.29 (2015): 10390-10401. PMC4510283
|
Western Blot; Rat |
Zhang, Ximei et al. “Increased 4-Hydroxynonenal Formation Contributes to Obesity-Related Lipolytic Activation in Adipocytes.” Ed. Anindita Das. PLoS ONE 8.8 (2013): e70663. PMC3734238
|
Western Blot; Mouse |
Publishing research using PPD3B-140AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PPD3B.140 | |||
|
PPD3B-140AP | |||
|
PPD3B.140-FITC | |||
|
PC-PPD3B | |||
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(c) FabGennix International Inc.