General Information |
|
Product |
Timeless Antibody BIOTIN |
Description |
BIOTIN-Conjugated Protein timeless homolog isoform 2 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide:
SGTPRVHRKKRFQIEDEDD
coresponding to amino acids 1178-1197 on Mouse Timeless protein. |
Accession # |
NCBI: NP_035719.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.98-1.26 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication and in the regulation of the circadian clock. Involved in the determination of period length and in the DNA damage-dependent phase advancing of the circadian clock. |
Molecular Function |
Developmental protein, protein heterodimerization activity, protein homodimerization activity |
Subcellular Location |
Nucleus |
Expression |
Predominantly and robustly expressed in proliferative organs (spleen, thymus, intestine and testis) compared to those more differentiated such as kidney and liver (at protein level). Expressed in all tissues examined including brain, heart, lung, liver, skeletal muscle, kidney, placenta, pancreas, spleen, thymus and testis. |
Structure |
Homodimer or homomultimer. |
Alternative Nomenclature |
Protein timeless homolog antibody TIM antibody timeless circadian clock 1 antibody TIMELESS1 antibody Tof1 homolog antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-TMLS | |||
|
TMLS-101AP | |||
|
TMLS-FITC | |||
|
PC-TMLS | |||
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