General Information |
|
Product |
ergo-1 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Endogenous-RNAi deficient arGOnaute Antibody C-epitope |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Caenorhabditis elegans |
Immunogen |
Synthetic peptide taken within amino acid region 190-240 on C.elegans Endogenous-RNAi deficient arGOnaute. |
Accession # |
NCBI: NP_503362.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.62-0.68 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Argonaute protein required for gene silencing in the endogenous RNA interference (RNAi) pathway. Interacts with 26G small interfering RNAs (26G-siRNAs) and required for subsequent biogenesis of secondary 22G-siRNAs. May be involved in passenger strand cleavage of target 26G-siRNAs (PubMed: 22102828). |
Molecular Function |
Dead/H-box RNA helicase binding, nucleic acid binding, production of siRNA involved in RNA interference, regulation of translation, RNA interference. |
Subcellular Location |
Cytoplasm |
Structure |
Belongs to the argonaute family. Piwi subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain. |
Expression | Expressed in embryos and during larval development up to larval stage 2. |
Alternative Nomenclature |
Endogenous RNAi deficient argonaute antibody Ergo 1 antibody Hypothetical protein R09A1.1 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-ERGO1 | |||
|
ERGO-101AP | |||
|
ERGO1-FITC | |||
|
PC-ERGO1 | |||
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