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General Information
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Product
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Lamin B1 antibody - Nuclear Envelope Marker Antibody
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Description
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Affinity Purified B1 antibody - Nuclear Envelope Marker Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 450-500 on human Lamin-B1 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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| Immunohistochemistry |
1:50-1:150 |
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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P20700
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Overview
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Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
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Molecular Function
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phospholipase binding
structural molecule activity
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Subcellular Location
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Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side
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Expression
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Homodimer. Interacts with lamin-associated polypeptides IA, IB and 2. Interacts with SPAG4 and SEPT12.
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Structure
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Belongs to the intermediate filament family.
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Alternative Nomenclature
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ADLD antibody
lamin B1 antibody
LMN antibody
LMN2 antibody
LMNB antibody
Lmnb1 antibody
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Lamin B1 antibody - Nuclear Envelope Marker Antibody BIOTIN
Lamin B1 antibody - Nuclear Envelope Marker Antibody FITC
Lamin B1 antibody - Nuclear Envelope Marker Blocking Peptide
Lamin B1 antibody - Nuclear Envelope Marker Positive Control
