PD2A-101AP | Publications

FabGennix PDE2A Antibody has been used in 38 Publications

Applications: Confocal imaging, Confocal microscopy, FRET, Immunodepletion, Immunofluorescence, Immunohistochemistry, and Western blot

Reactivity: Bovine, Dog, Human, Monkey, Mouse, Rabbit, and Rat

Pathak, G., et al. "PDE11A negatively regulates lithium responsivity." Molecular Psychiatry (2016).

PMID: 27646265

Applications: Western Blot

Reactivity: Mouse

Vettel, Christiane, et al. "Phosphodiesterase 2 protects against catecholamine-induced arrhythmia and preserves contractile function after myocardial infarction." Circulation Research (2016).

PMID: 27799254

Applications: Western Blot

Reactivity: Mouse

Sprenger, Julia U., et al. "In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease." Nature communications 6 (2015).

PMID: 25917898

Applications: Western Blot

Reactivity: Mouse

Fields, Laura A., Andreas Koschinski, and Manuela Zaccolo. "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." Cellular signalling (2015).

PMID: 26475678

Applications: Confocal imaging, FRET, Western Blot

Reactivity: Rat

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015).

PMID: 25704994

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Rajagopal, Senthilkumar, et al. "Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation." Journal of Pharmacology and Experimental Therapeutics 352.3 (2015).

PMID: 25550199

Applications: Western Blot

Reactivity: Mouse

Rentsendorj, Otgonchimeg, Franco R. D'Alessio, and David B. Pearse. "Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages." Journal of leukocyte biology 96.5 (2014).

PMID: 25063878

Applications: Western Blot

Reactivity: Mouse

Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).

PMID: 24463006

Applications: Western Blot

Reactivity: Rat

Yougbaré, Issaka, et al. "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842.7 (2014).

PMID: 24631654

Applications: Immunohistochemistry, Western Blot

Reactivity: Mouse

Hiramoto, Kenichi, et al. "Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells." Cellular signalling 26.9 (2014).

PMID: 24705027

Applications: Western Blot

Reactivity: Human

MORITA, HIROSHI et al. “Characterization of Phosphodiesterase 2A in Human Malignant Melanoma PMP Cells.” Oncology Reports 29.4 (2013). 

PMCID: 3621658

Applications: Western Blot

Reactivity: Human

Brechbühl, Julien, Fabian Moine, and Marie-Christine Broillet. “Mouse Grueneberg Ganglion Neurons Share Molecular and Functional Features withC. Elegans Amphid Neurons.” Frontiers in Behavioral Neuroscience 7 (2013).

PMCID: 3856774

Applications: Immunohistochemistry

Reactivity: Mouse

Matsuo, Tomohiko, et al. "The wiring of Grueneberg ganglion axons is dependent on neuropilin 1." Development 139.15 (2012).

PMID: 22745317

Applications: Immunohistochemistry

Reactivity: Mouse

Stephenson, D. T., et al. "The distribution of phosphodiesterase 2A in the Rat brain." Neuroscience 226 (2012).

PMID: 23000621

Applications: Immunohistochemistry, Immunodepletion, Western Blot

Reactivity: Mouse

Hu, Fei et al. “Natriuretic Peptides Block Synaptic Transmission by Activating Phosphodiesterase 2A and Reducing Presynaptic PKA Activity.”Proceedings of the National Academy of Sciences of the United States of America 109.43 (2012).

PMCID: 3491473

Applications: Western Blot

Reactivity: Human

Rentsendorj, Otgonchimeg et al. “Knockdown of Lung Phosphodiesterase 2A Attenuates Alveolar Inflammation and Protein Leak in a Two-Hit Mouse Model of Acute Lung Injury.” American Journal of Physiology - Lung Cellular and Molecular Physiology 301.2 (2011).

PMID: 3154628

Applications: Confocal microscopy, Immunofluorescence, Immunohistochemistry

Reactivity: Mouse

Ückert, S, et al. "Expression And Distribution Of Key Enzymes Of The Cyclic GMP Signaling In The Human Clitoris: Relation To Phosphodiesterase Type 5 (PDE5)." International Journal Of Impotence Research 23.5 (2011).

PMID: 21697861

Applications: Immunohistochemistry

Reactivity: Human

van der Horst, Irene WJM, et al. "Expression and function of phosphodiesterases in nitrofen‐induced congenital diaphragmatic hernia in Rats." Pediatric pulmonology 45.4 (2010).

PMID: 20196107

Applications: Immunohistochemistry, Western Blot

Reactivity: Rat

Lin, David TS, et al. "Nitric oxide signaling via cGMP‐stimulated phosphodiesterase in striatal neurons." Synapse 64.6 (2010).

PMID: 20175220

Applications: Western Blot

Reactivity: Rat

Wang, Jianjie, Susan Bingaman, and Virginia H. Huxley. “Intrinsic Sex-Specific Differences in Microvascular Endothelial Cell Phosphodiesterases.” American Journal of Physiology - Heart and Circulatory Physiology 298.4 (2010):

PMCID: 2853420

Applications: Confocal microscopy, Immunofluorescence, Western Blot

Reactivity: Rat

Stephenson, Diane T. et al. “Immunohistochemical Localization of Phosphodiesterase 2A in Multiple Mammalian Species.” Journal of Histochemistry and Cytochemistry 57.10 (2009).

PMCID: 2746727

Applications: Immunohistochemistry, Western Blot

Reactivity: Dog, Human, Monkey, Rat

Spießberger, Beate, et al. "Cgmp-Dependent Protein Kinase II And Aldosterone Secretion." FEBS Journal 276.4 (2009).

PMID: 19154345

Applications: Immunohistochemistry

Reactivity: Bovine, Mouse

WitzenRath, Martin, et al. "Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia*." Critical care medicine 37.2 (2009).

PMID: 19114892

Applications: Western Blot

Reactivity: Human, Mouse

Masood, Anbrin et al. “Anxiolytic Effects of Phosphodiesterase-2 Inhibitors Associated with Increased cGMP Signaling.” The Journal of Pharmacology and Experimental Therapeutics 331.2 (2009).

PMCID: 2775258

Applications: Immunoprecipitation

Reactivity: Human

Tahseldar-Roumieh, Rima et al. “PDEs1-5 Activity and Expression in Tissues of Cirrhotic Rats Reveal a Role for Aortic PDE3 in NO Desensitization.” International Journal of Experimental Pathology 90.6 (2009).

PMCID: 2803251

Applications: Western Blot

Reactivity: Rat

Liu, Cambrian Y., Scott E. Fraser, and David S. Koos. "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." Journal of CompaRative Neurology 516.1 (2009).

PMID: 19565523

Applications: Immunofluorescence, Western Blot

Reactivity: Mouse

Dodd-o, Jeffrey M., et al. "The role of natriuretic peptide receptor-A signaling in unilateral lung ischemia-reperfusion injury in the intact Mouse." American Journal of Physiology-Lung Cellular and Molecular Physiology 294.4 (2008).

PMID: 18223163

Applications: Western Blot

Reactivity: Mouse

Schmidt, Eric P. et al. “Soluble Guanylyl Cyclase Contributes to Ventilator-Induced Lung Injury in Mice.” American Journal of Physiology - Lung Cellular and Molecular Physiology 295.6 (2008).

PMCID: 2604795

Applications: Western Blot

Reactivity: Mouse

Ares, Gustavo R. et al. “cGMP Decreases Surface NKCC2 Levels in the Thick Ascending Limb: Role of Phosphodiesterase 2 (PDE2).” American Journal of Physiology- Renal Physiology 295.4 (2008).

PMID: 2576138

Applications: Western Blot

Reactivity: Rat

Ares, Gustavo R., et al. "Biomolecular Control Mechanisms and Integration of Vascular and Tubular Function: cGMP decreases surface NKCC2 levels in the thick ascending limb: role of phosphodiesterase 2 (PDE2)." American Journal of Physiology-Renal Physiology 295.4 (2008).

PMID: 18684888

Applications: Immunofluorescence, Western Blot

Reactivity: Rat

Albrecht, Knut, et al. "Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the Human vagina: A potential forensic value?." Journal of forensic and legal medicine 14.5 (2007).

PMID: 17113813

Applications: Immunohistochemistry

Reactivity: Human

Walz, Andreas, et al. "Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F." Development 134.22 (2007).

PMID: 17942483

Applications: Immunofluorescence

Reactivity: Mouse

de Oliveira, Simone Kobe, et al. "Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor." Journal of Biological Chemistry 282.18 (2007).

PMID: 17329248

Applications: Immunofluorescence, Immunoprecipitation, Western Blot

Reactivity: Human, Mouse

Mongillo, Marco, et al. "Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway." Circulation research 98.2 (2006).

PMID: 16357307

Applications: Western Blot

Reactivity: Rabbit

XIE, Z. et al. “CELLULAR AND SUBCELLULAR LOCALIZATION OF PDE10A, A STRIATUM-ENRICHED PHOSPHODIESTERASE.” Neuroscience 139.2 (2006).

PMCID: 1464838

Applications: Western Blot

Reactivity: Rat

Seybold J, et. Al., Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability. Blood. 2005 May 1.

PMID: 15650061

Applications: Western Blot

Human: Rat

Netherton, Stuart J., and Donald H. Maurice. "Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migRation: implications in angiogenesis." Molecular pharmacology 67.1 (2005): 263-272.

PMID: 15475573

Applications: Western Blot

Reactivity: Bovine, Human