Bestrophin 3 Antibody

Product no.: BEST-301AP

$320.00

Description
Publications

General Information
Product	Bestrophin 3 Antibody
Verified Applications	CM, ELISA, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
Dot Blot	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:200
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q6H1V1
Overview	Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Molecular Function	Ion transport; Calcium, Chloride.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Expression	Skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
Structure	Belongs to bestrophin Family
Alternative Nomenclature	BEST 3 antibody Bestrophin3 antibody MGC13168 antibody MGC40411 antibody Vitelliform macular dystrophy 2-like protein 3 antibody VMD2L3 antibody

Protein information supplied by UniProt

Fabgennix Bestrophin 3 Antibody has been used in 6 Publications

Golubinskaya, V., et al. "Bestrophin‐3 is differently expressed in normal and injured mouse glomerular podocytes." Acta Physiologica (2015). PMID25912364

Electron Microscopy, Immunodepletion, Western Blot; Mouse

Jiang, Lei, et al. "Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells." Apoptosis 18.5 (2013): 556-565. PMID23468120

Western Blot; Rat

Lee, Wing-Kee, et al. "ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP." Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823.10 (2012): 1864-1876. PMID22705154

Immunofluorescence, Western Blot; Rat

Wang, Mi, et al. "Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation." Circulation 125.5 (2012): 697-707. PMID22215857

Western Blot; Rat

Broegger, Torbjoern, et al. "Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric small arteries." Cardiovascular research 91.4 (2011): 685-693. PMID21498420

Immunofluorescence, Immunohistochemistry, Western Blot; Rat

Matchkov, Vladimir V., et al. "Bestrophin-3 (Vitelliform Macular Dystrophy 2–Like 3 Protein) Is Essential for the cGMP-Dependent Calcium-Activated Chloride Conductance in Vascular Smooth Muscle Cells." Circulation research 103.8 (2008): 864-872. PMID18776041

Western Blot; Rat

Publishing research using BEST-301AP? Please let us know, we can cite the reference in this datasheet.

Accessories

Product

Note

Status

Price

Bestrophin 3 Antibody FITC

BEST3.1-FITC

$375.00 *

Bestrophin 3 Antibody BIOTIN

BEST3.1-BIOTIN

$375.00 *

Bestrophin 3 Blocking Peptide

P-BEST3.1

$155.00 *

Bestrophin 3 Positive Control

PC-BEST3

$200.00 *

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