General Information
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Product
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CCR6 Antibody FITC-Conjugated
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Description
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FITC-Conjugated C-C chemokine receptor type 6 Antibody
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on human C-C chemokine receptor type 6 protein.
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Accession #
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NCBI: NP_004358.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.68 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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P51684
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Overview
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Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
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Molecular Function
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G-protein coupled receptor; Transducer; C-C chemokine receptor activity
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Expression
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Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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BN 1 antibody
C C chemokine receptor type 6 antibody
CCR-6 antibody
CD196 antibody
Chemokine (C C motif) receptor 6 antibody
CKR 6 antibody
DRY6 antibody
G protein coupled receptor 29 antibody
GPR-CY4 antibody
LARC receptor antibody
Seven transmembrane receptor lymphocyte 22 antibody
STRL22 antibody
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