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General Information
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Product
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CD68 Antibody
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Description
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Affinity Purified CD68 / Macrosialin Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 240-290 on mouse CD68 / Macrosialin protein.
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Accession #
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NCBI: NP_055843
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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P31996
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Overview
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Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
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Molecular Function
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cellular response to organic substance
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Subcellular Location
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Endosome membrane; Single-pass type I membrane protein
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Expression
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Expressed in tissue macrophages and to a lesser extent in dendritic cells.
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Structure
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Belongs to the LAMP family.
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Alternative Nomenclature
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CD 68 antibody
CD68 antigen antibody
CD68 molecule antibody
DKFZp686M18236 antibody
gp11 antibody
Gp110 antibody
LAMP4 antibody
MACROPHAGE ANTIGEN CD68 antibody
Macrosialin antibody
SCARD1 antibody
Scavenger receptor class D member 1 antibody
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CD68 Antibody BIOTIN
CD68 Antibody FITC
CD68 Blocking Peptide
CD68 Positive Control
