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General Information
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Product
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N-Chimaerin Antibody
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Description
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Affinity Purified N-Chimaerin isoform 1 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on alpha 2 Chimaerin protein.
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Accession #
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NCBI: NP_001813
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.58-0.63 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P15882
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Overview
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GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
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Molecular Function
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GTPase activation
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Subcellular Location
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Cytosol
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Expression
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In neurons in brain regions that are involved in learning and memory processes.
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Structure
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Interacts with EPHA4; effector of EPHA4 in axon guidance linking EPHA4 activation to RAC1 regulation.
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Alternative Nomenclature
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A-chimaerin antibody
Alpha-chimerin antibody
ARHGAP2 antibody
CHN antibody
Chn1 antibody
N chimaerin antibody
NC antibody
Rho GTPase-activating protein 2 antibody
RHOGAP2 antibody
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Chimaerin alpha 2 Antibody FITC
Chimaerin alpha 2 Antibody BIOTIN
Chimaerin alpha 2 Blocking Peptide
Chimaerin alpha 2 Positive Control
