Chimaerin alpha 2 Antibody

General Information

Product

N-Chimaerin Antibody

Description

Affinity Purified N-Chimaerin isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on alpha 2 Chimaerin protein.

Accession #

NCBI:  NP_001813

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P15882

Overview

GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.

Molecular Function

GTPase activation

Subcellular Location

Cytosol

Expression

In neurons in brain regions that are involved in learning and memory processes.

Structure

Interacts with EPHA4; effector of EPHA4 in axon guidance linking EPHA4 activation to RAC1 regulation.

Alternative Nomenclature

A-chimaerin antibody

Alpha-chimerin antibody

ARHGAP2 antibody

CHN antibody

Chn1 antibody

N chimaerin antibody

NC antibody

Rho GTPase-activating protein 2 antibody

RHOGAP2 antibody