General Information
|
|
Product
|
N-Chimaerin Antibody
|
Description
|
Affinity Purified N-Chimaerin isoform 1 Antibody
|
Verified Applications
|
ELISA, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide corresponding to unique amino acid sequence on alpha 2 Chimaerin protein.
|
Accession #
|
NCBI: NP_001813
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.58-0.63 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P15882
|
Overview
|
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
|
Molecular Function
|
GTPase activation
|
Subcellular Location
|
Cytosol
|
Expression
|
In neurons in brain regions that are involved in learning and memory processes.
|
Structure
|
Interacts with EPHA4; effector of EPHA4 in axon guidance linking EPHA4 activation to RAC1 regulation.
|
Alternative Nomenclature
|
A-chimaerin antibody
Alpha-chimerin antibody
ARHGAP2 antibody
CHN antibody
Chn1 antibody
N chimaerin antibody
NC antibody
Rho GTPase-activating protein 2 antibody
RHOGAP2 antibody
|
|
|