Dnmt3a Antibody

General Information

Product

Dnmt3a Antibody

Description

Affinity Purified DNA (cytosine-5)-methyltransferase 3A Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids within region 100-150 on mouse DNA (cytosine-5)-methyltransferase 3A protein.

Physical Properties

Quantity

100 µg

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Conjugate

Unconjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:100

Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O88508

Subcellular Location

Chromosome, Cytoplasm, Nucleus

Expression

Isoform 1 is expressed ubiquitously at low levels. Expression of isoform 2 is restricted to tissues containing cells which are undergoing active de novo methylation, including spleen, testis and thymus.

Structure

The PWWP domain is essential for targeting to pericentric heterochromatin. It specifically recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).

Alternative Nomenclature

DNA (cytosine 5) methyltransferase 3 alpha antibody

DNA (cytosine 5) methyltransferase 3A antibody

DNA cytosine methyltransferase 3A2 antibody

DNA methyltransferase 3 alpha antibody

DNA methyltransferase HsaIIIA antibody

DNA MTase HsaIIIA antibody

DNM3A_HUMAN antibody

DNMT 3a antibody

DNMT antibody

DNMT3A2 antibody

M.HsaIIIA antibody

MCMT antibody

OTTHUMP00000201149 antibody

TBRS antibody