ENT1 Antibody

Product no.: ENT1-101AP

$285.00

Description

General Information
Product	ENT1 Antibody
Description	Affinity Purified Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid reigon 410-460 on mouse Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 protein.
Accession #	GenBank: AAF64035.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q9JIM1
Overview	Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs).
Molecular Function	Nucleoside transmembrane transporter activity
Subcellular Location	Cell membrane; Basolateral cell membrane; Apical cell membrane
Expression	Highly expressed in heart, spleen, lung, liver and testis. Lower level of expression in brain and kidney.
Structure	Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
Alternative Nomenclature	Equilibrative NBMPR-sensitive nucleoside transporter antibody Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter antibody Equilibrative nucleoside transporter 1 antibody es-type antibody Nucleoside transporter, es-type antibody Slc29a1 antibody solute carrier family 29 (equilibrative nucleoside transporter), member 1 antibody Solute carrier family 29 member 1 antibody

Protein information supplied by UniProt