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General Information
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Product
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FBXW4 / SHFM3 Antibody Affinity Purified
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Description
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Affinity Purified F-box and WD-40 domain protein 4 Antibody
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Verified Applications
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DB, ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 240-290 on human FBX4 protein.
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Accession #
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GenBank: AAH07380.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68-0.7 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:4,000
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ELISA
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1:4,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P57775
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Overview
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Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
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Molecular Function
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Developmental Protein
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Subcellular Location
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Ubiquitin ligase complex
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Expression
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Expressed in brain, kidney, lung and liver.
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Structure
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Part of a SCF (SKP1-cullin-F-box) protein ligase complex
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Alternative Nomenclature
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DAC antibody
Dactylin antibody
F box and WD 40 domain containing protein 4 antibody
F box/WD repeat protein 4 antibody
F-box/WD repeat-containing protein 4 antibody
FBW 4 antibody
FBWD4 antibody
SHFM 3 antibody
SHSF3 antibody
Split hand/foot malformation (ectrodactyly) type antibody
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FBXW4 Antibody FITC
FBXW4 Antibody BIOTIN
FBXW4 Blocking Peptide
FBXW4 Positive Control
