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General Information
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Product
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FOXO3 Antibody
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Description
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Affinity Purified Forkhead box protein O3 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 620-670 on human Forkhead box protein O3.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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| Immunohistochemistry |
1:50-1:100 |
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Immunoprecipitation
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1:150
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Western Blot
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1:500. Apparent MW is 71 kDa.
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Protein
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Uniprot #
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O43524
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Overview
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Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
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Molecular Function
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Activator
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Subcellular Location
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Cytoplasm, Nucleus
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Expression
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Ubiquitous
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Structure
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Contains 1 fork-head DNA-binding domain.
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Alternative Nomenclature
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AF6q21 antibody
FKHR2 antibody
FKHRL 1 antibody
FKHRL1 antibody
Forkhead box protein O3 antibody
Forkhead box protein O3A antibody
Forkhead Drosophila homolog of in rhabdomyosarcoma like 1 antibody
Forkhead in rhabdomyosarcoma like 1 antibody
FOX O3A antibody
FOXO2 antibody
foxo3 antibody
FOXO3A antibody
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FOXO3A Antibody BIOTIN
FOXO3A Antibody FITC
FOXO3A Blocking Peptide
FOXO3A Positive Control
