General Information
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Product
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Factor VIII Antibody FITC-Conjugated
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Description
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FITC-Conjugated coagulation factor VIII Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within amino acid region 200-250 on human Coagulation Factor VIII protein.
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Accession #
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GenBank: CBL59398.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.75-0.95 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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D5H408
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Overview
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Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
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Molecular Function
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Copper ion binding; oxidoreductase activity
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Subcellular Location
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Secreted > extracellular space
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Structure
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Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.
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Alternative Nomenclature
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AHF antibody
Antihemophilic factor antibody
Coagulation factor VIII antibody
coagulation factor VIII, procoagulant component antibody
DXS1253E antibody
F8 antibody
F8b antibody
F8c antibody
factor VIII F8B antibody
Factor VIIIa light chain antibody
FactorVIII antibody
FVIII antibody
Hema antibody
Hemophilia A antibodyProcoagulant component antibody
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