General Information
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Product
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GDF8 / Myostatin Antibody BIOTIN
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Description
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BIOTIN-Conjugated Myostatin Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 325-375 on human Myostatin.
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Accession #
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GenBank: ABI48514
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q53S46
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Overview
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Acts specifically as a negative regulator of skeletal muscle growth.
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Molecular Function
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Cytokine activity; Growth factor activity; heparin binding; identical protein binding; receptor binding; transforming growth factor beta receptor binding
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Subcellular Location
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Secreted; cytoplasm
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Structure
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Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3. Belongs to the TGF-beta family.
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Alternative Nomenclature
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GDF 8 antibody
Growth differentiation factor 8 antibody
MSLHP antibody
MSTN antibody
myostatin antibody
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