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General Information
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Product
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hopQ Antibody
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Description
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Affinity Purified hopQ H. Pylori Antibody
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Verified Applications
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CM, ELISA, ICC, IF, IP, IHC, WB
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Host
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Rabbit
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Species Cross Reactivity
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Heliobacter pylori
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Immunogen
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Heat killed and denatured Heliocobacter pylori extracts
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Accession #
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Accession: WP_202143412
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.80-1.35 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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ELISA
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1:5,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:300
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Immunohistochemistry
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1:200
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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J0TJV0
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Overview
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Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection.
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Molecular Function
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polyubiquitin binding, Rab GTPase binding, protein C-terminus binding
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Subcellular Location
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Cytoplasm › perinuclear region. Golgi apparatus. Golgi apparatus › trans-Golgi network. Cytoplasmic vesicle ›autophagosome. Cytoplasmic vesicle. Recycling endosome
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Expression
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Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta.
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Structure
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Interacts with HD, Rab8 (RAB8A and/or RAB8B) (active GTP-bound form), GTF3A, TRAF3, TBK1, MYO6 and TFRC. Binds to linear ubiquitin chains. Interacts with LC3 family members MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2; OPTN phosphorylation increas
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Alternative Nomenclature
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H. pylori antibody
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hopQ H. Pylori Antibody FITC
hopQ H. Pylori Antibody BIOTIN
hopQ H. Pylori Blocking Peptide
hopQ H. Pylori Positive Control
