ITK Antibody BIOTIN

General Information

Product

ITK Antibody BIOTIN

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 550-600 on human ITK protein.

Accession #

GenBank: BAA02873.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54-0.57 µg/µl in antibody stabilization buffer

Form

BIOTIN-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q08881

Overview

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells.

Molecular Function

ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity

Subcellular Location

Cytoplasm (Note: Localizes in vicinity of cell surface receptors in plasma membrane after receptor stimulation)

Expression

T-cell lines and natural killer cell lines.

Alternative Nomenclature

EMT antibody

Homolog of mouse T cell itk/tsk antibody

IL 2 inducible T cell kinase antibody

Itk antibody

Kinase EMT antibody

LPFS1 antibody

LYK antibody

MGC126257 antibody

MGC126258 antibody

PSCTK 2 antibody

T cell specific kinase antibody

TSK antibody

Tyrosine protein kinase antibody

Tyrosine protein kinase ITK/TSK antibody