Lin28 Antibody

Product no.: LIN28-101AP

$285.00

Description

General Information
Product	Lin28 Antibody
Description	Affinity Purified LIN28 protein Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid sequence 1-60 on Lin28A sequence.
Accession #	GenBank: AAH28566.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.88-0.95 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q9H9Z2
Overview	Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Association with translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing mRNA's
Molecular Function	DNA binding, mRNA binding, zinc ion binding, miRNA binding, RNA binding
Subcellular Location	Cytoplasm, nucleus, nucleolus. (Note: nucleolar localization observed in 10-15% of nuclei in differentiated byotubes. Shuttles between cytoplasm and nucleus. Localizes to cytoplasmic processing bodies and stress granules)
Expression	Expressed in embryonic stem cells (ES cells), placenta and testis.
Alternative Nomenclature	AL024421 antibody CSDD1 antibody FLJ12457 antibody Lin 28 antibody Protein lin-28 homolog A antibody RNA binding protein lin 28 antibody Tex17 antibody ZCCHC1 antibody Zinc finger CCHC domain containing 1 antibody

Protein information supplied by UniProt