Alpha Synuclein Antibody

Product no.: NACP-101AP
$285.00


General Information

 

 

Product

 

alpha Synuclein Antibody

Description

Affinity Purified alpha-synuclein isoform NACP112 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 62-112 unique sequence on alpha-synuclein isoform NACP 112 protein.

Specificity This antibody will not detect NACP140.

Accession #

NCBI: NP_009292


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Purification Method Immobilized antigen affinity chromatography.
Immunoglobulin IgG

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:20,000

ELISA

1:20,000

Immunohistochemistry 1:100
Immunoprecipitation 1:200

Western Blot

1:500


Protein

 

Uniprot #

 

P37840

Overview

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Molecular Function

Alpha-tubulin binding, Calcium-ion binding, copper ion binding

Subcellular Location

cytoplasm, Membrane, Nucleus, Cell junction > synapse

Expression

Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Structure

Soluble monomer which can form filamentous aggregates. Interacts with UCHL1. Interacts with phospholipase D and histones

Alternative Nomenclature

Alpha synuclein 

MGC105443 

MGC110988 

MGC127560 

NACP 

PARK 1 

PARK 4 

PD 1 

SNCA 

SYN 

   

Protein information supplied by UniProt

Accessories

Product Note Status Price
Alpha Synuclein Antibody FITC Alpha Synuclein Antibody FITC
NACP-FITC $375.00 *
Alpha Synuclein Antibody BIOTIN Alpha Synuclein Antibody BIOTIN
NACP-BIOTIN $375.00 *
Alpha Synuclein Blocking Peptide Alpha Synuclein Blocking Peptide
P-NACP $155.00 *
Alpha Synuclein Positive Control Alpha Synuclein Positive Control
PC-NACP $200.00 *
Display accessory details

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