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General Information
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Product
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Occludin Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 450-523 on rat Occludin protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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Q6P6T5
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Overview
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May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. May be involved in the organization of actin in endothelial cells.
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Molecular Function
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protein domain specific binding
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Subcellular Location
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Cell membrane
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Structure
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he C-terminal is cytoplasmic and is important for interaction with ZO-1. Sufficient for the tight junction localization. Involved in the regulation of the permeability barrier function of the tight junction.
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Alternative Nomenclature
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BLCPMG antibody
Occludin antibody
Ocln antibody
OCLN_HUMAN antibody
Phosphatase 1 regulatory subunit 115 antibody
PPP1R115 antibody
PTORCH1 antibody
Tight junction protein occludin antibody
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Occludin Antibody BIOTIN
Occludin Antibody FITC
Occludin Blocking Peptide
Occludin Positive Control
