5HT2C Receptor Blocking Peptide

General Information

Product

5HT2C Receptor Peptide

Description

Antigenic Blocking Peptide 5-hydroxytryptamine receptor 2C Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P28335

Overview

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Multi-pass membrane protein

Expression

Detected in brain.

Structure

The PDZ domain-binding motif is involved in the interaction with PATJ, CASK, APBA1, DLG1 and DLG4.

Alternative Nomenclature

5 Hydroxytryptamine 2C receptor antibody
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody
5-hydroxytryptamine receptor 1C antibody
5-hydroxytryptamine receptor 2C antibody
5HT1C antibody
5HT2C antibody
5HTR2C antibody
5Hydroxytryptamine 2C receptor antibody
Htr1c antibody
HTR2C antibody
serotonin 1c receptor antibody
serotonin 2c receptor antibody
Serotonin receptor 2C antibody