ABL2 Blocking Peptide

Product no.: P-ABL2

$155.00

Description

General Information
Product	ABL2 Peptide
Description	Antigenic Blocking Peptide Tyrosine-protein kinase ABL2 Antibody
Verified Applications	Immunodepletion, Immunocompetition
Peptide Description	Synthetic peptide corresponding to amino acids within region 1100-1150 on human Tyrosine-protein kinase ABL2 / ARG.
Physical Properties
Quantity	250 µg
Volume	100 µl
Form	Antigenic Blocking Peptide
Storage	-20?C for long term storage
Application Protocol
Immunodepletion, Immunocompetition	Refer to competition assay protocol
Protein
Uniprot #	P42684
Overview	Non-receptor tyrosine-protein kinase that plays an ABL1-overlapping role in key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion and receptor endocytosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like MYH10 (involved in movement); CTTN (involved in signaling); or TUBA1 and TUBB (microtubule subunits). Binds directly F-actin and regulates actin cytoskeletal structure through its F-actin-bundling activity. Involved in the regulation of cell adhesion and motility through phosphorylation of key regulators of these processes such as CRK, CRKL, DOK1 or ARHGAP35.
Molecular Function	actin filament binding actin monomer binding ATP binding magnesium ion binding manganese ion binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein kinase activity protein tyrosine kinase activity
Subcellular Location	Cytoskeleton
Expression	Widely expressed.
Alternative Nomenclature	Abelson murine leukemia viral oncogene homolog 2 antibody Abelson related gene protein antibody Abelson tyrosine-protein kinase 2 antibody Abelson-related gene protein antibody ABL2 antibody ABL2_HUMAN antibody ABLL antibody ARG antibody Tyrosine kinase ARG antibody Tyrosine protein kinase ABL2 antibody Tyrosine-protein kinase ARG antibody v abl Abelson murine leukemia viral oncogene homolog 2 antibody

Protein information supplied by UniProt.