AMPK alpha 1 Blocking Peptide

Product no.: P-AMPK1

$155.00

Description

General Information
Product	AMPK alpha 1 Peptide
Description	Antigenic Blocking Peptide 5'-AMP-activated protein kinase catalytic subunit alpha-1
Verified Applications	Immunodepletion, Immunocompetition
Peptide Description	Synthetic peptide taken within amino acid region 500-550 on rat 5'-AMP-activated protein kinase catalytic subunit alpha-1 protein.
Physical Properties
Quantity	250 µg
Volume	100 µl
Form	Antigenic Blocking Peptide
Storage	-20⁰C for long term storage
Application Protocol
Competition/Depletion assay	Refer to competition assay protocol
Protein
Uniprot #	P54645
Overview	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.
Molecular Function	[acetyl-CoA carboxylase] kinase activity [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity AMP-activated protein kinase activity ATP binding chromatin binding
Subcellular Location	Nucleus, Cytoplasm
Expression	Low expression in kidney, liver, lung, heart and brain.
Structure	The AIS (autoinhibitory sequence) region shows some sequence similarity with the ubiquitin-associated domains and represses kinase activity.
Alternative Nomenclature	5 AMP activated protein kinase alpha 1catalytic subunit antibody AAPK1 antibody ACACA kinase antibody acetyl CoA carboxylase kinase antibody AMP -activate kinase alpha 1 subunit antibody AMPK 1 antibody AMPK alpha 1 antibody HMG CoA reductase kinase antibody HMGCR kinase antibody hormone sensitive lipase kinase antibody Hydroxymethylglutaryl CoA reductase kinase antibody im:7154392 antibody kinase AMPK alpha1 antibody PRKAA 1 antibody Protein kinase AMP activated alpha 1 catalytic subunit antibody SNF1A antibody Tau protein kinase PRKAA1 antibody

Protein information supplied by UniProt.