Bestrophin Blocking Peptide

General Information

Product

Bestrophin Peptide

Description

Antigenic Blocking Peptide Bestrophin 1 Antibody C-epitope

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid reigon 500-585 on human Bestrophin-1 isoform 1 protein.

Accession #

NCBI:  NP_004174

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

O76090

Overview

Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.

Molecular Function

Ion transport; Sensory transduction; Transport; Vision

Subcellular Location

Cell membrane; Multi-pass membrane protein; Basolateral cell membrane

Expression

Predominantly expressed in the basolateral membrane of the retinal pigment epithelium

Structure

Tetramer or pentamers

Alternative Nomenclature

ARB antibody

BEST 1 antibody

BEST antibody

Best disease antibody

BEST1 antibody

Bestrophin1 antibody

BMD antibody

mBest1 antibody

RP50 antibody

TU15B antibody

Vitelliform macular dystrophy 2 antibody

VMD2 antibody