CXCR2 Blocking Peptide

General Information

Product

CXCR2 Peptide

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide

EDLSNYSYSSTLPPFLLDAAPC

Amino acids 18-39

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P25025

Overview

Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils.  This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system.

Molecular Function

G-Protein coupled receptor, Transducer, chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Up-regulated by CREB3

Structure

Binds to HIV-1 Tat and interacts with ARRB1

Alternative Nomenclature

C-X-C chemokine receptor type 2 antibody

CD 182 antibody

CD182 antigen antibody

CDw128b antibody

Chemokine (CXC) receptor 2 antibody

CMKAR2 antibody

CXCR2 antibody

GRO/MGSA receptor antibody

High affinity interleukin-8 receptor B antibody

IL8R B antibody

IL8R2 antibody

IL8RA antibody

Interleukin 8 receptor, beta antibody

Interleukin 8 receptor, type 2 antibody