DWORF Blocking Peptide

General Information

Product

DWORF Peptide

Description

Antigenic Blocking Peptide Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synththetic peptide corresponding to full length Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P0DN83

Overview

Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca2+ uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN).

Molecular Function

Sarcoplasmic reticulum membrane; Single-pass membrane protein

Alternative Nomenclature

Dwarf open reading frame antibody,DWORF antibody,Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORFSERCA regulator DWORF antibody,