|
General Information
|
|
|
Product
|
Prostaglandin E2 receptor EP3 subtype Antibody Antigenic Blocking Peptide
|
|
Description
|
Antigenic Blocking Peptide Prostaglandin E2 Receptor subtype isoform 7
|
|
Verified Applications
|
Immunocompetition, Immunodepletion
|
|
Peptide Description
|
Synthetic peptide taken within amino acid region 300-350 on human Prostaglandin E2 receptor EP3 subtype.
|
|
Accession #
|
NCBI: NP_942010.1
|
|
Physical Properties
|
|
|
Quantity
|
250 µg
|
|
Volume
|
100 µl
|
|
Form
|
Antigenic Blocking Peptide
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
|
Protein
|
|
Uniprot #
|
P43115
|
|
Overview
|
Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
|
|
Molecular Function
|
Prostaglandin E receptor activity, G-protein coupled receptor
|
|
Subcellular Location
|
Cell membrane; Multi-pass membrane
|
|
Expression
|
Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
|
|
Structure
|
Belongs to the G-protein coupled receptor 1 family.
|
|
Alternative Nomenclature
|
EP 2 antibody
Human prostaglandin E2 receptor antibody
PGE2 receptor EP2 subtype antibody
Prostaglandin E receptor 2 EP2 subtype antibody
PTGER2 antibody
|
| |
|
Prostaglandin E Receptor EP2 Antibody
Prostaglandin E Receptor EP2 Antibody FITC
Prostaglandin E Receptor EP2 Antibody BIOTIN
Prostaglandin E Receptor EP2 Positive Control
