EPAC2 Blocking Peptide

General Information

Product

Epac2 Peptide

Description

Antigenic Blocking Peptide Rap Guanine Nucleotide Exchange Factor 3 

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein.

Sequence:

CPREQFDSLTPLPEQEGPT

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9Z1C7

Overview

Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).

Molecular Function

Guanine-nucleotide releasing factor

Subcellular Location

Cytoplasm; Membrane; Peripheral membrane protein

Structure

Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A (By similarity).

Alternative Nomenclature

CAMP GEFII antibody

cAMP regulated guanine nucleotide exchange factor II antibody

CGEF2 antibody

Epac 2 antibody

Exchange protein directly activated by cAMP 2 antibody

Nbla00496 antibody

Putative protein product of Nbla00496 antibody

Rap guanine nucleotide exchange factor (GEF) 4 antibody

RAPGEF 4 antibody