GPCR GPR7 Blocking Peptide

General Information

Product

GPCR GPR7 Peptide

Description

Antigenic Blocking Peptide Neuropeptides B/W receptor type 1 Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 1-50 on human neuropeptides B/W receptor type 1 protein.

Accession #

NCBI:  NP_005276

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P48145

Overview

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

G protein coupled receptor 7 
GPR7 
MGC129755 
Neuropeptides B and W receptor 1 
NPB and NPW receptor 1 
NPBWR1 
opioid somatostatin like receptor 7