GPCR GPR8 Blocking Peptide

General Information

Product

GPCR GPR8 Peptide

Description

Antigenic Blocking Neuropeptide B/W receptor type 2 Peptide

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 280-333 on human Neuropeptides B/W receptor type 2 protein.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

1:500

Protein

Uniprot #

P48146

Overview

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.

Molecular Function

G-protein coupled receptor, Receptor, Transducer.

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Expression

Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

G protein coupled receptor 8 
GPR8 
Neuropeptides B/W receptor type 2 
NPBWR2