HIF-1-Alpha isoform 1 + 2 Blocking Peptide

General Information

Product

HIF-1-Alpha isoform 1 + 2 Peptide

Description

Antigenic Blocking Peptide Hypoxia-inducible factor 1-alpha isoform 2 Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken wtihin amino acid region 150-250 on human HIF1A protein.

Accession #

NCBI:  NP_851397.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q16665

Overview

Functions as a master transcriptional regulator of the adaptive response to hypoxia.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

highest levels in kidney and heart;common human cancers and their metastases, due to the presence of intratumoral hypoxia

Structure

Heterodimer

Alternative Nomenclature

ARNT interacting protein antibody

Basic-helix-loop-helix-PAS protein MOP1 antibody

bHLHe78 antibody

Class E basic helix-loop-helix protein 78 antibody

HIF 1A antibody

HIF 1alpha antibody

Hypoxia inducible factor 1 alpha antibody

Member of PAS protein 1 antibody

Member of PAS superfamily 1 antibody

MOP1 antibody

PAS domain-containing protein 8 antibody

PASD8 antibody