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General Information
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Product
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Helicobacter pylori Blocking Peptide
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Heat killed and denatured Helicobacter pylori extracts
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q96CV9
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Overview
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Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection.
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Molecular Function
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polyubiquitin binding, Rab GTPase binding, protein C-terminus binding
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Subcellular Location
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Cytoplasm › perinuclear region. Golgi apparatus. Golgi apparatus › trans-Golgi network. Cytoplasmic vesicle ›autophagosome. Cytoplasmic vesicle. Recycling endosome
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Expression
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Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta.
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Structure
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Interacts with HD, Rab8 (RAB8A and/or RAB8B) (active GTP-bound form), GTF3A, TRAF3, TBK1, MYO6 and TFRC. Binds to linear ubiquitin chains. Interacts with LC3 family members MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2; OPTN phosphorylation increas
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Alternative Nomenclature
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H. pylori antibody
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Helicobacter pylori Antibody
Helicobacter pylori Antibody FITC
Helicobacter pylori Antibody BIOTIN
Helicobacter pylori Positive Control
