Integrin linked ILK Blocking Peptide

General Information

Product

ILK Peptide

Description

Antigenic Blocking Peptide Integrin-linked protein kinase Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 400-452 on human Integrin-linked protein kinase.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q13418

Overview

Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.

Molecular Function

ATP binding, protein kinase binding, protein serine/threonine kinase activity, signal transducer activity

Subcellular Location

Cell junction, cell membrane, peripheral membrane protein, cytoplasmic side, cell projection

Expression

Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.

Alternative Nomenclature

59 kDa serine/threonine protein kinase antibody

DKFZp686F1765 antibody

ILK 1 antibody

ILK 2 antibody

ILK antibody

Integrin linked kinase 2 antibody

Integrin-linked protein kinase antibody

p59 antibody

p59ILK antibody