PDE11A3 Blocking Peptide

General Information

Product

PDE11A3 Peptide

Description

Antigenic Blocking Peptide Phosphodiesterase 11A3 Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic Peptide

Accession #

GenBank: AB038041.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9HCR9

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.

Molecular Function

Hydrolase, metal-ion binding, cGMP binding

Subcellular Location

Cytoplasm

Expression

Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil  is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed

Alternative Nomenclature

PDE11A antibody

PDE11A3 antibody

PPNAD2 antibody