PDE1A Blocking Peptide

General Information

Product

PDE1A Peptide

Description

Antigenic Blocking Peptide Phosphodiesterase 1A Antibody C-epitope

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide corresponding to unique amino acid sequence within amino acid region 51-101 on PDE1A protein. Common to all PDE1A variants.

Accession #

NCBI:  NP_001009978.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Immunoglobulin

IgG

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9JLL9

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.

Molecular Function

Hydrolase, calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity, metal ion binding

Subcellular Location

Cytosol

Expression

Several tissues, including brain, kidney, testes and heart.

Structure

Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.

Alternative Nomenclature

3' 5' cyclic nucleotide phosphodiesterase antibody
5''-cyclic nucleotide phosphodiesterase 1A antibody
61 kDa Cam PDE antibody
Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1A antibody
Calcium/Calmodulin stimulated cyclic nucleotide phosphodiesterase antibody
Calcium/calmodulin-dependent 3'' antibody
Calmodulin-dependent Phosphodiesterase antibody
Cam PDE 1A antibody
HCAM1 antibody
HSPDE1A antibody
MGC26303 antibody
PDE1A antibody
Phosphodiesterase 1A antibody
Phosphodiesterase 1A calmodulin dependent antibody