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General Information
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Product
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PDE4D8 Peptide
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Description
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Antigenic Blocking Peptide cAMP-specific phosphodiesterase PDE4D8 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic Peptide
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Accession #
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GenBank: AAN10119.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q08499
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Molecular Function
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Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Subcellular Location
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Apical cell membrane, Cytoplasm, Membrane
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Expression
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Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
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Structure
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Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protei
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Alternative Nomenclature
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cAMP-specific 3'5'-cyclic phosphodiesterase 4D antibody
DPDE3 antibody
dunce-like phosphodiesterase E3 antibody
hPDE4D5 antibody
PDE4D antibody
PDE4DN2 antibody
Phosphodiesterase 4D antibody
Phosphodiesterase 4D cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) antibody
Phosphodiesterase 4D cAMP-specific antibody
STRK1 antibody
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PDE4D8 Antibody
PDE4D8 Antibody FITC
PDE4D8 Antibody BIOTIN
PDE4D8 Positive Control
