TIA1 Blocking Peptide

General Information

Product

TIA1 Antibody Antigenic Blocking Peptide

Description

Antigenic Blocking Peptide Nucleolysin TIA-1 isoform p40 Antibody

Verified Applications

Immunocompeition, Immunodepletion

Peptide Description

Synthetic Peptide

Accession #

GenBank: BAD92448.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:50

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:50

Competition/Depletion assay

1:500

Protein

Uniprot #

P31483

Overview

Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Molecular Function

AU-rich element binding, nucleotide binding, poly(A) binding, poly (A) RNA binding

Subcellular Location

Cytoplasmic granule, nucleus. (Note: accumulates in cytoplasmic stress granules following cellular damage

Alternative Nomenclature

Cytotoxic granule associated RNA binding protein 1 antibody

Nucleolysin TIA 1 isoform p40 antibody

p40 TIA 1 antibody

p40-TIA-1 (containing p15-TIA-1) antibody

RNA binding protein TIA 1 antibody

T-cell-restricted intracellular antigen-1 antibody

TIA 1 cytotoxic granule associated RNA binding protein antibody

TIA1 cytotoxic granule associated RNA binding protein like 1 antibody

TIA1 protein antibody

TIAL1 antibody

TIAR antibody