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General Information
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Product
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PAR2 Antibody
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Description
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Affinity Purified Proteinase-activated receptor 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Chimpanzee, Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 300-370 of mouse PAR2.
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| Specificity |
This antibody is directed against a cytoplasmic region of PAR2. |
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Accession #
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NCBI: NP_032000.3
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.62 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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| Purification Method |
Immobilized antigen affinity chromatography. |
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:15,00-1:20,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:200
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Western Blot
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1:250
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Protein
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Uniprot #
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P55086
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Overview
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Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
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Molecular Function
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G-protein coupled receptor, Receptor, Transducer
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Expression
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Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
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Structure
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Interacts with TLR4, COPS5 and TMED2. Also interacts with GNAQ, GNA11, GNA12, GNA13, and GNA14.
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Alternative Nomenclature
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Coagulation factor II receptor like 1
Coagulation factor II thrombin receptor like 1
F2RL1
G protein coupled receptor 11
GPR11
PAR 2
Proteinase activated receptor 2
Thrombin receptor like 1
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PAR2 Antibody FITC
PAR2 Antibody BIOTIN
PAR2 Blocking Peptide
PAR2 Positive Control
