General Information
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Product
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PAX8 Antibody
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Description
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Affinity Purified Paired box protein Pax-8 Antibody N-epitope
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 120-170 on human PAX8 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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QO6710
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Overview
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Is a transcription factor for the thyroid specific expression of the genes expressed solely in the thyroid cell type. It maintains the funcitonal differentiation of cells such as those.
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Molecular Function
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DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, Developmental protein
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Subcellular Location
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Nucleus
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Expression
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Is expressed in the excretory system, thyroid gland and Wilms tumors.
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Structure
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Interacts with WWTR1
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Alternative Nomenclature
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Paired box 8 antibody
Paired domain gene 8 antibody
PAX8 antibody
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