General Information
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Product
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LIMK1 Positive Control
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Description
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Western Blot Positive Control LIM domain kinase 1
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Verified Applications
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WB
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Accession #
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NCBI: NP_002305.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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P53667
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Overview
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Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways.
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Molecular Function
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ATP binding, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding, heat shock protein binding
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Subcellular Location
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Cytoplasm, nucleus
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Expression
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Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
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Alternative Nomenclature
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EC 2.7.11.1 antibody
LIM domain kinase 1 antibody
LIM motif-containing protein kinase antibody
LIMK antibody
LIMK-1 antibody
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