ARMET Positive Control

General Information

Product

ARMET Positive Control

Description

Western Blot Positive Control Mesencephalic astrocyte-derived neurotrophic factor Antibody

Verified Applications

WB

Immunogen

Synthetic peptide taken within amino acid region 80-120 on human Mesencephalic astrocyte-derived neurotrophic factor.

Accession #

NCBI:  NP_006001

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P55145

Overview

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.

Molecular Function

Growth factor

Subcellular Location

Secreted, Endoplasmic reticulum, Extracellular space, Nucleus

Expression

By endoplasmic reticulum stress.

Structure

The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.

Alternative Nomenclature

Arginine rich mutated in early stage tumors antibody
Arginine rich protein antibody
ARMET antibody
ARP antibody
Manf antibody
Mesencephalic astrocyte derived neurotrophic factor antibody