General Information |
|
Product |
PDE11A4 Antibody Western Blot Positive Control |
Description |
Western Blot Positive Control Phosphodiesterase 11A4 Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: BAB62712.1 |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
Molecular Function |
Hydrolase, 3', 5'-cyclic-GMP phosphodiesterase activity, cGMP binding |
Subcellular Location |
Cytoplasm |
Expression |
Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i |
Alternative Nomenclature |
cGMP phosphodiesterase 11A antibody Pde11a antibody Pde11A2 antibody Pde11A3 antibody PDE11A4 antibody Phosphodiesterase 11A antibody PPNAD2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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PD11A4-131AP | |||
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PD11A4-FITC | |||
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P-PD11A4 | |||
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PD11A4-BIOTIN | |||
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