Phospho-Protein vestigial Positive Control

General Information

Product

Protein Vestigial Antibody Western Blot Positive Control

Description

Western Blot Positive Control Vestigial Antibody

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_523723.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q26366

Overview

Involved in determining which thoracic imaginal disk cells will form wings and halteres, perhaps by interacting with other nuclear regulatory proteins. When in combination with scalloped (sd), it acts as a transcriptional activation complex that regulates gene expression in the wing. Binding to sd switches the DNA target selectivity of sd. Required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk. Also required for cell proliferation in the wing imaginal disk, mediated via activation of E2f. By interacting with Dhfr, may control genes involved in DNA replication.

Molecular Function

DNA binding; Protein C-terminus binding

Subcellular Location

Nucleus

Expression

Expressed in the developing wing primordia initially along the D/V wing boundary, and by the late third larval instar, maximal expression is seen in cells at the D/V wing disk boundary. Less expression is seen in cells located farther from this boundary.

Alternative Nomenclature

VG

VSTGL

VG21

DMEL/CG3830

CCG3830