TdT Positive Control

General Information

Product

TdT Positive Control

Description

Western Blot Positive Control DNA nucleotidylexotransferase

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_004079

Physical Properties

Quantity

5 Applications

Volume

Inquire

Immunoglobulin

IgG

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:1,000

Protein

Uniprot #

P04053

Overview

Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Molecular Function

Nucleotidyltransferase, Transferase, DNA binding

Subcellular Location

Nucleus

Structure

Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA.

Alternative Nomenclature

Deoxynucleotidyltransferase terminal antibody
DNA nucleotidylexotransferase antibody
DNTT antibody
Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody
TDT antibody
Terminal addition enzyme antibody
Terminal deoxynucleotidyltransferase antibody
Terminal transferase antibody