PDE4A11 Antibody

Product no.: PD4A11-161AP

$320.00

Description

1_21

General Information
Product	PDE4A11 Antibody Affinity Purified
Description	Affinity Purified Phosphodiesterase 4A11 Antibody N-epitope
Verified Applications	ELISA, IMM, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	Synthetic peptide taken within amino acid region 50-100 on human PDE4A11 protein.
Accession #	GenBank: AAU82096
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.45-0.65 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	P27815
Overview	Hydrolyzes the second messenger cAMP which is a key regulator of many important physiological processes.
Molecular Function	cAMP
Subcellular Location	Isoform 1: perinuclear region, Isoform 2: ruffle membrane, Isoform 4: Peripheral membrane protein, Isoform 6: perinuclear region, Isoform 7: Membrane, Cytoplasm
Expression	Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Iso
Structure	Belongs to cyclic nucleotide phosphodiesterase family. PDE4 subfamily
Alternative Nomenclature	5''-cyclic phosphodiesterase 4A11 antibody PDE46 antibody phosphodiesterase 4A11 cAMP specific antibody phosphodiesterase isozyme 4A11 antibody phosphodiesterase type 4A11 antibody

Protein information supplied by UniProt