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General Information
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Product
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PDE8B Antibody
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Description
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Affinity Purified Phosphodiesterase 8B Antibody
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Verified Applications
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CM, ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bovine, Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic cyclic peptide common to all PDE8B variants.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Immunoprecipitation
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1:250
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Western Blot
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1:500-1:2,000
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Protein
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Uniprot #
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E9PXX4
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
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Molecular Function
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3',5'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding
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Expression
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Widely expressed
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PER-ARNT-SIM (PAS) domain.
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Alternative Nomenclature
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3' 5' cyclic nucleotide phosphodiesterase 8B antibody
Cell proliferation-inducing gene 22 protein antibody
FLJ11212 antibody
High affinity cAMP specific and IBMX insensitive 3' 5' cyclic phosphodiesterase 8B antibody
HSPDE 8B antibody
PDE8B antibody
Phosphodiesterase8B antibody
PIG22 antibody
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PDE8B Antibody FITC
PDE8B Antibody BIOTIN
PDE8B Blocking Peptide
PDE8B Positive Control
