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General Information
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Product
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cGKI Antibody
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Description
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Affinity Purified cGMP-dependent protein kinase 1 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 609-659 on human protein kinase G alpha subunit.
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Accession #
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NCBI: NP_001091982.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q13976
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Overview
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Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Cytoplasm
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Expression
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Primarily expressed in lung and placenta
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Structure
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Isoform alpha: parallel homodimer or heterodimer and also heterotetramer. Interacts directly with PPP1R12A. Non-covalent dimer of dimer of PRKG1-PRKG1 and PPP1R12A-PPP1R12A.
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Alternative Nomenclature
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cGK 1 antibody
cGKI alpha antibody
CGKI antibody
cGKI beta antibody
cGMP-dependent protein kinase 1 antibody
DKFZp686K042 antibody
FLJ36117 antibody
KGPB antibody
MGC71944 antibody
pkg antibody
PRKG1 antibody
PRKGR1A antibody
PRKGR1B antibody
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cGKI Antibody FITC
cGKI Antibody BIOTIN
cGKI Blocking Peptide
cGKI Positive Control
