PTBP2 Antibody

Product no.: PTBP2-101AP

$285.00

Description

General Information
Product	PTBP2 Antibody
Description	Affinity Purified Polypyrimidine tract-binding protein 2 / PTBP2 Antibody
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 150-200 on human Polypyrimidine tract-binding protein 2 / PTBP2.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5-1.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20C for long term storage
Application Protocol
ELISA	1:50,000
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q9UKA9
Overview	RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Molecular Function	mRNA binding RNA binding
Subcellular Location	Nucleus
Expression	Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform
Alternative Nomenclature	brPTB antibody FLJ34897 antibody MIBP antibody Neural polypyrimidine tract binding protein antibody Neural polypyrimidine tract-binding protein antibody Neurally enriched homolog of PTB antibody Neurally-enriched homolog of PTB antibody nPTB 5 antibody nPTB 6 antibody nPTB 7 antibody nPTB 8 antibody nPTB antibody nPTB5 antibody nPTB6 antibody nPTB7 antibody nPTB8 antibody Polypyrimidine tract binding protein 2 antibody Polypyrimidine tract-binding protein 2 antibody PTB antibody PTB like antibody PTB like protein antibody PTB-like protein antibody PTBLP antibody PTBP 2 antibody Ptbp2 antibody PTBP2_HUMAN antibody Splicing regulator antibody

Protein information supplied by UniProt.