RUNX3 Antibody

Product no.: RUNX3-301AP

$285.00

Description

1_438

General Information
Product	RUNX3 Antibody Affinity Purified
Description	Affinity Purified Runt-related transcription factor 3 Antibody N-epitope
Verified Applications	ELISA, IMM, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1-50 on human Runt-related transcription factor 3 protein.
Accession #	NCBI: NP_001026850.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.52-0.53 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q13761
Overview	CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters.
Molecular Function	ATP binding, RNA polymerase II regulatory region sequence-specific DNA binding
Subcellular Location	Nucleus, cytoplasm
Structure	Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1.
Alternative Nomenclature	Acute myeloid leukemia 2 protein antibody AML2 antibody CBF alpha 3 antibody CBFA 3 antibody Core binding factor alpha 3 subunit antibody core binding factor antibody Core binding factor runt domain alpha subunit 3 antibody Core-binding factor subunit alpha-3 antibody FLJ34510 antibody MGC16070 antibody Oncogene AML 2 antibody PEA2 alpha C antibody PEBP2 alpha C antibody Pebp2a3 antibody PEBP2aC antibody Polyomavirus enhancer binding protein 2 alpha C subunit antibody runt domain alpha subunit 3 antibody runt related transcription factor 3 antibody RUNX 3 antibody SL3 3 enhancer factor 1 alpha C subunit antibody SL3/AKV core binding factor alpha C subunit antibody Transcription factor AML2 antibody

Protein information supplied by UniProt