TRPM8 Antibody

Product no.: TRPM8-101AP

$285.00

Description

General Information
Product	TRPM8 Antibody Affinity Purified
Description	Affinity Purified Transient receptor potential cation channel subfamily M member 8 Antibody
Verified Applications	ELISA, WB
Host	Rabbit
Species Cross Reactivity	Rat, Mouse
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on TRPM8 protein.
Accession #	NCBI: NP_599198.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.6 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Western Blot	1:500
Protein
Uniprot #	Q8R455
Overview	Involved in detection of sensations such as coolness, activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH
Molecular Function	Calcium channel activity
Subcellular Location	cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts)
Expression	Expressed in dorsal root and trigeminal ganglia. Specifically expressed in a subset of sensory neurons, including cold-sensitive neurons in trigeminal neurons.
Alternative Nomenclature	Long transient receptor potential channel 6 antibody LTrpC6 antibody Short form of the TRPM8 cationic channel antibody Transient receptor potential cation channel subfamily M member 8 antibody Transient receptor potential p8 antibody TRPP8 antibody

Protein information supplied by UniProt